Metoclopramide
Metoclopramide works by accelerating the emptying of the stomach and the motility of the entire intestinal tract. It also affects receptors in the brain that suppress nausea and vomiting.
Common side effects include drowsiness and diarrhea.
If you have not had an electrocardiogram (ECG) within the last 2 years, you must have one taken before starting treatment.
Metoclopramide tablets are 10 mg; you may take a maximum of 3 tablets per day.
Domperidone
Domperidone works by accelerating the emptying of the stomach and the motility of the entire intestinal tract.
Common side effects include dry mouth and diarrhea.
If you have not had an electrocardiogram (ECG) within the last 2 years, you must have one taken before starting treatment.
Domperidone tablets are 10 mg; you may take a maximum of 3 tablets per day.
Domperidone is also available as suppositories. They are 30 mg, must be prepared at the pharmacy, and are therefore relatively expensive. You may take a maximum of 1 suppository per day.
Ondansetron
Ondansetron works by blocking the vomiting reflex both in the body and in the brain.
Common side effects include headache and constipation.
If you have not had an electrocardiogram (ECG) within the last 2 years, you must have one taken before starting treatment.
Ondansetron tablets are 4 mg or 8 mg; you may take a maximum of 2 tablets per day.